Breast Cancer in Women Using Breast Implants
Impact on Diagnosis and Treatment
DOI:
https://doi.org/10.56226/101Keywords:
Breast Cancer, Breast Implants, Mammography, Radiotherapy, ChemotherapyAbstract
Introduction: Breast cancer is one of the most common diseases among women, and early diagnosis is essential for effective treatment. The use of breast implants can introduce additional challenges in the diagnosis and treatment of breast cancer.
Methodology: A literature review was conducted to investigate the impact of breast implants on the diagnosis and treatment of breast cancer. Studies on the effectiveness of different imaging methods (mammography, magnetic resonance imaging, and ultrasound) and therapeutic approaches (surgery, radiotherapy, and chemotherapy) in women with breast implants were analyzed, as well as the psychological impact of diagnosis and treatment.
Results: The results show that breast implants can make it difficult to visualize the entire breast tissue on mammograms. However, advanced techniques such as MRI and ultrasound can improve diagnostic accuracy. In treatment, the presence of implants can influence surgical approaches and the administration of radiotherapy, requiring careful planning. The psychological impact of diagnosis and treatment on women with implants is significant, highlighting the importance of emotional support.
Conclusion: The use of breast implants presents unique challenges in the diagnosis and treatment of breast cancer. With advanced imaging techniques and personalized therapeutic approaches, it is possible to effectively manage these challenges. Collaboration between radiologists, surgeons, oncologists and psychologists is essential to ensure the best possible care for these patients, providing effective and humane treatment.
References
Bijlard, E., & Mureau, M. A. M. (2021). Implant Surface Texture and Breast Cancer Recurrence. JAMA surgery, 10.1001/jamasurg.2021.0691. Advance online publication. https://doi.org/10.1001/jamasurg.2021.0691
Bright, R. A., Jeng, L. L., & Moore, R. M. (1993). National survey of self-reported breast implants: 1988 estimates. Journal of long-term effects of medical implants, 3(1), 81–89.
Brinton, L. A., Lubin, J. H., Burich, M. C., Colton, T., Brown, S. L., & Hoover, R. N. (2001). Cancer risk at sites other than the breast following augmentation mammoplasty. Annals of epidemiology, 11(4), 248–256. https://doi.org/10.1016/s1047-2797(00)00223-4
Cole S. W. (2009). Chronic inflammation and breast cancer recurrence. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27(21), 3418–3419. https://doi.org/10.1200/JCO.2009.21.9782
da Silva Barreto, G., Brito do Nascimento, J., Cristina Santos de Almeida, K., Carlos Marcolino Neto, J., & Lucas Ferreira Luz da Silva, S. (2024). The CRISPR therapy: A revolutionary breakthrough in genetic medicine. International Healthcare Review (online). https://doi.org/10.56226/88
de Andrade Urban, C., Cavalcante, F. P., & El-Tamer, M. B. (2021). Implant Surface Texture and Breast Cancer Recurrence. JAMA surgery, 10.1001/jamasurg.2021.0688. Advances online publication. https://doi.org/10.1001/jamasurg.2021.0688
de Boer, M., van Leeuwen, F. E., Hauptmann, M., Overbeek, L. I. H., de Boer, J. P., Hijmering, N. J., Sernee, A., Klazen, C. A. H., Lobbes, M. B. I., van der Hulst, R. R. W. J., Rakhorst, H. A., & de Jong, D. (2018). Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast. JAMA oncology, 4(3), 335–341. https://doi.org/10.1001/jamaoncol.2017.4510
De Cholnoky T. (1970). Augmentation mammaplasty. Survey of complications in 10,941 patients by 265 surgeons. Plastic and reconstructive surgery, 45(6), 573–577.
de Jong, D., Vasmel, W. L., de Boer, J. P., Verhave, G., Barbé, E., Casparie, M. K., & van Leeuwen, F. E. (2008). Anaplastic large-cell lymphoma in women with breast implants. JAMA, 300(17), 2030–2035. https://doi.org/10.1001/jama.2008.585
de Vries, C. E. E., Kaur, M. N., Klassen, A. F., Sommers, K., Hume, K. M., & Pusic, A. L. (2022). Understanding Breast Implant-Associated Illness: A Delphi Survey Defining Most Frequently Associated Symptoms. Plastic and reconstructive surgery, 149(6), 1056e–1061e. https://doi.org/10.1097/PRS.0000000000009088
Deapen, D. M., Pike, M. C., Casagrande, J. T., & Brody, G. S. (1986). The relationship between breast cancer and augmentation mammaplasty: an epidemiologic study. Plastic and reconstructive surgery, 77(3), 361–368. https://doi.org/10.1097/00006534-198603000-00001
H€olmich LR, Mellemkjær L, Gunnarsdottir KA, Tange UB, Krag C, Møller S, McLaughlin JK, Olsen JH. Stage of breast cancer at diagnosis among women with cosmetic breast implants. Br J Cancer 2003; 88:832–8.
Hu, H., Johani, K., Almatroudi, A., Vickery, K., Van Natta, B., Kadin, M. E., Brody, G., Clemens, M., Cheah, C. Y., Lade, S., Joshi, P. A., Prince, H. M., & Deva, A. K. (2016). Bacterial Biofilm Infection Detected in Breast Implant-Associated Anaplastic Large-Cell Lymphoma. Plastic and reconstructive surgery, 137(6), 1659–1669. https://doi.org/10.1097/PRS.0000000000002010
IARC. Monographs on the evaluation of carcinogenic risks to humans. Surgical implants and other foreign bodies. vol. 74. Lyon: IARC, 1999.
Instituto Nacional do Câncer. Consulta de dados médicos (PDQ). Prevenção do Câncer de Mama. 2023. https://www.cancer.gov/types/prostate/hp/prostate-prevention-pdq
Kouwenberg, C. A. E., de Ligt, K. M., Kranenburg, L. W., Rakhorst, H., de Leeuw, D., Siesling, S., Busschbach, J. J., & Mureau, M. A. M. (2020). Long-Term Health-Related Quality of Life after Four Common Surgical Treatment Options for Breast Cancer and the Effect of Complications: A Retrospective Patient-Reported Survey among 1871 Patients. Plastic and reconstructive surgery, 146(1), 1–13. https://doi.org/10.1097/PRS.0000000000006887
Lee, K. T., Kim, S., Jeon, B. J., Pyon, J. K., Mun, G. H., Ryu, J. M., Lee, S. K., Yu, J., Kim, S. W., Lee, J. E., Nam, S. J., & Bang, S. I. (2020). Association of the Implant Surface Texture Used in Reconstruction With Breast Cancer Recurrence. JAMA surgery, 155(12), 1132–1140. https://doi.org/10.1001/jamasurg.2020.4124
Loch-Wilkinson, A., Beath, K. J., Magnusson, M. R., Cooter, R., Shaw, K., French, J., Vickery, K., Prince, H. M., & Deva, A. K. (2020). Breast Implant-Associated Anaplastic Large Cell Lymphoma in Australia: A Longitudinal Study of Implant and Other Related Risk Factors. Aesthetic surgery journal, 40(8), 838–846. https://doi.org/10.1093/asj/sjz333
Maarse, W., & Teunis, T. (2021). Implant Surface Texture and Breast Cancer Recurrence. JAMA surgery, 10.1001/jamasurg.2021.0694. Advance online publication. https://doi.org/10.1001/jamasurg.2021.0694
Maluf, G., Vianna, A., Kenupp, M. G., & Uyeda, M. (2024). Clinical pathological features and radiotherapy treatment for adenoid cystic carcinoma of the head and neck: An Update on recent evidence. International Healthcare Review (online). https://doi.org/10.56226/79
Marinho, S., Brito, M., & Clarindo, Ítalo A. L. P. (2025). The Influence of Cancer on the Sexual and Emotional Health of Young People: A Longitudinal Analysis. International Healthcare Review (online). https://doi.org/10.56226/94
Marques da Silva, M., Matias Cunha, C., Aquino, C., Aquino, L., & Fernanda Pizo Ferreira, P. (2025). SBRT for Uncomplicated Bone Metastases in the Spine from Lung Cancer: A literature Review. International Healthcare Review (online). https://doi.org/10.56226/92
McLaughlin, J. K., Nyrén, O., Blot, W. J., Yin, L., Josefsson, S., Fraumeni, J. F., Jr, & Adami, H. O. (1998). Cancer risk among women with cosmetic breast implants: a population-based cohort study in Sweden. Journal of the National Cancer Institute, 90(2), 156–158. https://doi.org/10.1093/jnci/90.2.156
Mennie, J. C., Mohanna, P. N., O'Donoghue, J. M., Rainsbury, R., & Cromwell, D. A. (2017). National trends in immediate and delayed post-mastectomy reconstruction procedures in England: A seven-year population-based cohort study. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 43(1), 52–61. https://doi.org/10.1016/j.ejso.2016.09.019
Morgan, R. W., & Elcock, M. (1995). Artificial implants and soft tissue sarcomas. Journal of clinical epidemiology, 48(4), 545–549. https://doi.org/10.1016/0895-4356(94)00211-8
Panchal, H., & Matros, E. (2017). Current Trends in Postmastectomy Breast Reconstruction. Plastic and reconstructive surgery, 140(5S Advances in Breast Reconstruction), 7S–13S. https://doi.org/10.1097/PRS.0000000000003941
Pierce, B. L., Ballard-Barbash, R., Bernstein, L., Baumgartner, R. N., Neuhouser, M. L., Wener, M. H., Baumgartner, K. B., Gilliland, F. D., Sorensen, B. E., McTiernan, A., & Ulrich, C. M. (2009). Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27(21), 3437–3444. https://doi.org/10.1200/JCO.2008.18.9068
Kenupp, M. G., Vianna, A., Uyeda, M., & Maluf, G. (2024). On Patients with Colorectal Cancer : Associations, prognosis, survival and effects of therapy performed in the intestinal microbiota. International Healthcare Review (online). https://doi.org/10.56226/83 R
ohrich, R. J., & Clark, C. P., 3rd (1993). Controversy over the silicone gel breast implant: current status and clinical implications. Texas medicine, 89(9), 52–58.
Sahoo, S., Rosen, P. P., Feddersen, R. M., Viswanatha, D. S., Clark, D. A., & Chadburn, A. (2003). Anaplastic large cell lymphoma arising in a silicone breast implant capsule: a case report and review of the literature. Archives of pathology & laboratory medicine, 127(3), e115–e118. https://doi.org/10.5858/2003-127-e115-ALCLAI
Salvans, S., Mayol, X., Alonso, S., Messeguer, R., Pascual, M., Mojal, S., Grande, L., & Pera, M. (2014). Postoperative peritoneal infection enhances migration and invasion capacities of tumor cells in vitro: an insight into the association between anastomotic leak and recurrence after surgery for colorectal cancer. Annals of surgery, 260(5), 939–944. https://doi.org/10.1097/SLA.0000000000000958
Silva Ribeiro, L., & Cristina Uniat, K. (2025). On Public Health and New Prostate Cancer Screening Strategies: Comparison of Methods and Results for Prevention. International Healthcare Review (online). https://doi.org/10.56226/97
Song, C., & Xie, H. (2023). On Disparities in Breast Cancer Screening: An Analysis of Behavioral Risk Factor Surveillance Survey Data related to Racial/ Ethnic characteristics. International Healthcare Review (online). https://doi.org/10.56226/53
St Cyr, T. L., Pockaj, B. A., Northfelt, D. W., Craig, F. E., Clemens, M. W., & Mahabir, R. C. (2020). Breast Implant-Associated Anaplastic Large-Cell Lymphoma: Current Understanding and Recommendations for Management. Plastic surgery (Oakville, Ont.), 28(2), 117–126. https://doi.org/10.1177/2292550320925906
van Bommel, A. C. M., de Ligt, K. M., Schreuder, K., Maduro, J. H., Van Dalen, T., Peeters, M. T. F. D. V., Mureau, M. A. M., Siesling, S., & NABON Breast Cancer Audit Working Group (2020). The added value of immediate breast reconstruction to health-related quality of life of breast cancer patients. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 46(10 Pt A), 1848–1853. https://doi.org/10.1016/j.ejso.2020.06.009
Uyeda, M. (2022). On a Global Agenda for Oncology Research: From Biomarker studies to post-genomic technologies. International Healthcare Review (online), 1(1). https://doi.org/10.56226/ihr.v1i1.9
Watad, A., Rosenberg, V., Tiosano, S., Cohen Tervaert, J. W., Yavne, Y., Shoenfeld, Y., Shalev, V., Chodick, G., & Amital, H. (2018). Silicone breast implants and the risk of autoimmune/rheumatic disorders: a real-world analysis. International journal of epidemiology, 47(6), 1846–1854. https://doi.org/10.1093/ije/dyy217
Zijiu, C., Li, W., & Qin, J. (2025). Philosophical Reflections on Chinese Naturopathy against Malignant Tumours. International Healthcare Review (online). https://doi.org/10.56226/99
Downloads
Published
How to Cite
License
Copyright (c) 2025 The Publisher
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
Start-up >