Neonatal Hypoglycemia: exploring incidence and risk factors

Authors

  • Rui Huang Department of Nursing, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
  • Yunfeng Li Department of Nursing, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
  • Yuehua Guo Department of Nursing, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China.

DOI:

https://doi.org/10.56226.89

Keywords:

neonatal hypoglycemia; morbidity; risk factor, neonatal, nursing, morbidity, risk factors, public health

Abstract

Introduction: Neonatal hypoglycemia is one of the most common metabolic problems in newborns, which can lead to brain damage and increase the risk of developmental delay.
Objectives: The aim of this study was to determine the incidence of neonatal hypoglycemia in neonates and to identify associated risk factors using data from one major hospital in one Province of China. The application of this study in clinical settings can help professionals early identify high risk newborn and give individualized prevention and intervention measures, which may in turn help reduce
the incidence rate of neonatal hypoglycemia and reduce complications caused by
hypoglycemia.
Methodology: Case control study was used on newborns who gave birth between 2016 and 2021 in China. Authors developed a case-control study at a tertiary hospital database between Jan 1, 2016 and Jan 2021. The Cases were identified on the basis of having an outcome of hypoglycemia. Four controls per case (1:4) were randomly selected. Then, multivariable logistic regression analysis was used to analyze risk factors related to the incidence of neonatal hypoglycemia.
Results: 16.8% (255) newborns in the cohort had hypoglycemia within 24 hours of birth. Besides, logistic regression analyses showed that cesarean section(OR:3.800,95%CI:8.223-23.158), maternal diabetes(OR:7.416,95%CI:4.287-12.828), maternal hypertension(OR:8.019,95%CI:3.933-16.348), small for gestational age(OR:3.894,95%CI:1.428-10.622), neonatal hypothermia(OR:17.130,95%CI:10.899-26.925) and neonatal infection(OR:17.038,95%CI:5.520-52.590) were risk factors for neonatal hypoglycemia.
Conclusion: In a contemporary cohort, the incidence of neonatal hypoglycemia is relatively high, and the incidence of neonatal hypoglycemia is significantly correlated with various clinical factors. Monitoring these risk factors is one of the important measures to reduce the adverse consequences caused by neonatal hypoglycemia.

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Published

31-12-2024

How to Cite

Huang, R., Li, Y., & Guo, Y. (2024). Neonatal Hypoglycemia: exploring incidence and risk factors. International Healthcare Review (online). https://doi.org/10.56226.89

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