What is Long COVID-19?
Clarifying Definitions and Symptoms.
DOI:
https://doi.org/10.56226/ihr.v1i2.28Keywords:
Long Covid-19, Sars-CoV-2, Definition, SymptomsAbstract
Background:
What is the definition of Long COVID-19? What are its currently acknowledged symptoms? As this is a new condition suspected to be evolving as a potentially post-Pandemic new disease, it becomes relevant to clarify the current definitions of Long COVID-19. The article puts together the most recent definitions and briefly discusses points of common understanding and points of uncertainty.
Objectives:
The main aim of the article is to clarify the definitions and symptoms of Long COVID-19 as international evidence defines them. This is relevant to support health professionals and interested parties to access a structured clarification of the disease at this stage of knowledge. Supporting evidence-based intervention is the fundamental objective of the article.
Methods:
The Rapid Literature Review is a form of evidence synthesis that provides timely information for decision making and evidence-based practice compared with standard systematic reviews. The review used the following sources: Web of Science and PubMed,. The Search used the keywords ‘Long Covid-19’, ‘Definitions’ and ‘Symptoms’ and limited to articles published between January 2021 and June 2022. There were two reviewers to select articles based on the inclusion/exclusion criteria (keywords defined and time span of publications). Both reviewers appraised critically and rigorously within the criteria defined and a summary was produced.
Results:
Six articles were identified as relevant for the objectives of this article. These were individually evaluated on the contribution to clarifying definitions and symptoms of Long COVID-19. Definitions seem to follow the initial definition made available in a publication from World Health Organization. However, the follow-up articles seem to add additional interpretations and associated symptoms.
Main Contribution to Evidence-Based Practice:
The article puts together the recent evolution of the definition of Long COVID-19 and associated symptoms to support clinical decision-making and evidence-based practice.
References
Ahn DG, Shin HJ, Kim MH, et al. Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19).J Microbiol Biotechnol. 2020;30(3):313-324.
Aiyegbusi OL, Hughes SE, Turner G, et al. (2021) Symptoms, complications and management of long COVID: a review. J R Soc Med. 2021;114(9):428-442.
Chen C, Haupert SR, Zimmermann L, Shi X, Fritsche LG, Mukherjee B. (2022) Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review. J Infect Dis. 2022.
Choutka J, Jansari V, Hornig M, Iwasaki A. (2022) Unexplained post-acute infection syndromes. Nat Med. 2022;28(5):911-923.
Fong Liew M, Ting Siow W, MacLaren G, et al. Preparing for COVID-19: early experience from an intensive care unit in Singapore. Crit Care. 2020;24:83.
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet, 2020;395:497-506
Lamontagne SJ, Winters MF, Pizzagalli DA, Olmstead MC (2021) . Post-acute sequelae of COVID-19: Evidence of mood & cognitive impairment. Brain Behav Immun Health. 2021;17:100347.
Lloyd Williams, D. (2022). On Healthcare Research Priorities in the USA : From Long COVID to Precision Health, what else is new?. International Healthcare Review (online), 1(1). https://doi.org/10.56226/ihr.v1i1.14
Omboni S, Ballatore T, Rizzi F, et al. Telehealth at scale can improve chronic disease management in the community during a pandemic: an experience at the time of COVID-19. PLoS One. 2021;16(9):e0258015.
Rigoni M, Torri E, Nollo G, et al. (2021) "Long COVID" results after hospitalization for SARS-CoV-2 infection. Sci Rep. 2022;12(1):9581.
Sifuentes-Rodrıguez E, Palacios-Reyes D. COVID-19: The outbreak caused by a new coronavirus. Bol Med Hosp Infant Mex. 2020;77(2):47-53.
Tricco, A.C., Antony, J., Zarin, W. et al. A scoping review of rapid review methods. BMC Med 13, 224 (2015). https://doi.org/10.1186/s12916-015-0465-6
WHO (2021) Organization WH. A clinical case definition of post COVID-19 condition by a Delphi consensus. WHO REFERENCE NUMBER: WHO/2019-nCoV/Post_COVID-19_condition/Clinical_case_definition/2021.1. Retrieved July 2, 2022 from https://www.who.int/publications/i/item/WHO-2019-nCoV-Post_COVID-19_condition-Clinical_case_definition-2021.1

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